Übersetzung für "Nonspecifically" in Deutsch

Nonspecifically bound antiserum was then removed by washing 3 times with solution 2.

By this method IgG and IgG complexes are nonspecifically removed from the blood of patients.

Thereafter, rinsing was carried out with ethanol in order to remove nonspecifically adsorbed APS.

These nonspecifically reacting substances are often antibodies.

This prevents the indication of higher values by the TBA method as the result of the otherwise nonspecifically increased 5-hydroxymethyl-furfural formation.

Thereafter, the cover slips were rinsed with ethanol in order to remove nonspecifically adsorbed 3-glycidoxypropyltrimethoxysilane.

In addition, it is possible to demonstrate that intact bacteria do not bind calcein nonspecifically or take it up actively.

In addition to alkylating cytostatic agents and glucocorticoids, which inhibit cell proliferation nonspecifically, only heparin has hitherto been effective in this model following parenteral administration.

All PCRs were begun by means of “Hot Start”: after addition of all components of the PCR, except the polymerase, this was added only after heating the sample to 94° C., which strongly reduces the extension of nonspecifically binding primers.

The applied substances according to the invention possess the additional advantage that in contrast to many other substance classes and substances tested, they do not concentrate additionally and nonspecifically in other tissues and organs which is decisive for suitablility as a diagnostic.

The following primer sequences are used (only the specific part is listed; for equilibrating the annealing temperature, it is filled with nonspecifically binding positions (“wobbles”):

However, it is practically impossible to determine the number and length of the different fragments produced after an amplification conducted with two nonspecifically binding primers.

The immune complexes themselves are nonspecifically removed, not through protein A but through biomolecules, which, due to physiological reasons, have a high affinity to immunoglobulins.

However, the second receptor can also be a receptor binding nonspecifically with THP or the complex of first receptor and THP-binding receptor.

One begins with a PCR pre-amplification with at least one pair of primers of different sequence, which nonspecifically hybridize the pretreated DNA sample and thus more than one amplified product results in the PCR step.

One begins with a PCR preamplification with at least one pair of primers of different sequence, which hybridize nonspecifically to the pretreated DNA sample and thus produce more than one amplified product in the PCR step.

The classical cancer treatment with chemotherapy and/or irradiation brings many side effects, as the means generally nonspecifically affect the whole body.

In a further preferred embodiment, labeling is carried out by spatially-resolved addition of a marker, e.g. a specifically or nonspecifically binding optical marker, such as an intercalator (Sybergreen).

In an alternative embodiment labeling takes place by spatially-resolved addition of a marker, e.g. a specifically or nonspecifically binding optical marker, such as an intercalator (Sybergreen), and subsequent elution by the laser capture method, which is known by a person skilled in the art from the isolation of individual cells.

In particular, the method should enable the highly selective isolation of binding molecules against selected native target molecules, i.e. specifically only targeting one single target molecule, excluding a maximum of nonspecifically binding molecules without isolating the actual target molecule, including such target molecules with low copy numbers and such which e.g. are internalised after ligand formation through endocytosis.

In the afore-mentioned methods for detection of several antibody-fluorochrome conjugates it is disadvantageous that fluorochromes can emit light nonspecifically, for example after energy transfer from another fluorochrome, if several different fluorochromes are used simultaneously for the analysis of a sample.

The disadvantage is that not only do the desired cells take up the nanoparticle but also other (healthy cells) to which the nanoparticle is transported nonspecifically through the blood vessels.

Most chemotherapeutic agents administered parenterally today are not distributed to the tumor tissue or tumor cells in a targeted manner but instead are nonspecifically distributed throughout the patient's body through systemic administration, i.e., at sites where exposure to the drug is often undesirable, such as in healthy cells, tissues and organs, for example.

Depletion may take place specifically (by the displacement of the continuous phase or by the introduction of a separating layer for coarse/fine materials) or nonspecifically by the metering of diluting water in the cyclone.

Since proteins only bind nonspecifically to the unmodified support material, it is advantageous if as little background binding as possible occurs.

Thus, while melagatran, which possesses a 4-amidinobenzylamide residue C-terminally, inhibits trypsin (K i =2.0 nM) and thrombin (K i =2.0 nM) very nonspecifically, its inhibition of uPA, with a K i =6.3 ?M, is three orders of size weaker (D. Gustafsson et al., Blood Coagul.

The signals for c-Cbl-specific siRNA and nonspecifically transfected cells were very similar (low).