Translation of "Causal role" in German

The results of these experiments support the causal role of opportunity.

Disturbances of this activity of brain circuits will thus play a causal role in the pathogenesis and pathology of psychiatric disorders.

However, there is increasing evidence from long-term epidemiological studies that cannabis plays a causal role.

Other, non-karmic factors also play a causal role in the arising of a karmic result.

If manic or psychotic symptoms occur, consideration should be given to a possible causal role for methylphenidate, and discontinuation of treatment may be appropriate.

Consideration should be given to the exacerbation of an underlying psychiatric condition and to a possible causal role of methylphenidate treatment.

Regarding peritoneal and cardiac fibrosis, the CHMP was of the view that the causal role of nicergoline cannot be excluded.

Based on a cumulative review of data from all the MAHs, the causal role of paclitaxel for palmarplantar erythrodysesthesia syndrome is at least a reasonable possibility.

Regarding cases of pulmonary reactions, the emerging number of cases and the improvement observed after nicergoline discontinuation in 10 cases with no confounding factor is in favour of a causal role of nicergoline, especially in 5 cases in which improvement was also confirmed by radiography or scanner.

Based on a number of angioedema cases reported in relation to carfilzomib monotherapy or combination therapy, 5 of which with positive dechallenge, and the plausible mechanism considering possible class effect (bortezomib has angioedema included in section 4.8 of SmPC), as well as presented cases which suggest causal role of carfilzomib, the PRAC considers that the product information (PI) should be updated to include this adverse reaction.

Exposure to environmental and occupational factors – including pesticides, heavy metals, and solvents – probably play an important causal role, either independently or in tandem with a genetic predisposition to the disease.

Health indicators specify the data needs on disease occurrence, for those diseases which are significant public health problems, and for which the environment plays a significant causal role.

While limited information is available a causal role of influenza vaccine (surface antigen, inactivated, prepared in cell cultures) could not be completely excluded.

Of these 2 cases of torsade de pointes with positive dechallenge after dose reduction or discontinuation of rivastigmine, the causal role of rivastigmine due to its bradycardia-related adverse event could not be ruled out despite the confounding factors in these cases (venlafaxine, tiapride).

On account of those properties, the compounds of formula I and their pharmaceutically acceptable salts are excellently suitable for the therapeutic treatment of disorders in which excess production of IL-1 plays a causal or aggravating role, such as inflammatory and degenerative disorders of the joints, for example rheumatoid arthritis, osteoarthritis, psoriatic or infectious arthritis, of Reiter syndrome, of gout and traumatic arthritis, and of other acute or chronic inflammations, for example of inflammatory intestinal disorders, of meningitis, skin disorders, such as psoriasis, pemphigus vulgaris and the like, of allergic skin reactions, atherosclerosis and autoimmune disorders, such as diabetes (type 1) and thyroiditis.

In most of these cases, cocaine seems to have played a causal role, although this is not always entirely clear from the reports.

If the combustion chamber 4 is operated with a gaseous fuel, that is for example natural gas, the outlet temperature of the partly expanded hot gases 9 from the turbine 3 must still be very high, around 1000° C. as explained above, and this of course must also be the case during part-load operation, a factor which plays a causal role in the design of this turbine 3 .

Moreover it is assumed that H. pylori also plays a causal role in the development of gastric and duodenal ulcers (ulcus ventriculi and ulcus duodeni) as well as some forms of gastric carcinoma (adenocarcinoma) (Lee et al., 1993;

The connection of the expression of variant CD44 species with the metastatic potential in two series of rat tumours indicates a causal role of the glyco-proteins in the metastatic process.

Mainly, these are genes which play a crucial causal role in immunological complications, in inflammatory diseases, autoimmune disorders, septic shock, transplant rejection, thromboses or else alternatively in chronic inflammatory diseases such as arteriosclerosis, arthritis and rheumatism psoriasis.

For example, if all deaths with a positive toxicological examination are grouped together, this will include cases where drugs have played a direct causal role, an indirect role or no role at all.

However, the causal role of maternity leave legislation for first birth timing is uncertain, since transition rates to first birth began to diverge by employer tenure even before 1976."

He has also shown that the primary danger in the defilements is their causal role in sustaining the round of rebirths.

Hypercholesterolemia also plays a causal role in the pathogenesis of arteriosclerosis, liver cancer, xanthomatosis and many other disorders.

Starting from the assumption that the combustion chamber 9 is operated with a gaseous fuel, that is, for example, natural gas, the temperature of the hot exhaust gases 8 from the turbine 7 must be around 1000° C. for self-ignition, and this of course must also be the case during part-load operation, a factor which plays a causal role in the design of this turbine 7.