Translation of "Neurotropic" in German

He has neurotropic and calming effect on the central nervous system with increased irritability, insomnia, vegetative-vascular disorders.

Nervous system disorders Cases of neurotropic disease (known as YEL-AND), some of which have had a fatal outcome, have been reported following yellow fever vaccination (see section 4.4).

Additional information on special population Congenital or acquired immunodeficiency has been identified as a risk factor for neurotropic disease (See sections 4.3 and 4.4).

Interaction with neurotropic and other active substances through its activity on P 450-cytochrome has been reported (see section 4.5).

These properties are a true water solubility sufficient for producing stable, that is, not supersaturated, concentrated solutions, maximum general and neurotropic tolerance, minimum osmolality, slight viscosity, maximum stability towards hydrolytic effects and a sufficiently simple structure to make the synthesis economical as well as to simplify the isolation and purification.

It is evident that the neurotropic/spasmolytic effect predominates with the compounds according to the invention, while the undesired myotropic/spasmolytic effect predominates with the comparison compound.

Numerous substances which are based on a,a-diphenylacetic acids and which have found use in pharmacotherapy as neurotropic or myotropic spasmolytics have been described.

The neurotropic/spasmolytic effect of the succinyl ester compared to propiverine is investigated in vitro on an isolated preparation of guinea pig urinary bladder muscle by customary techniques.

It is found from these experiments that the succinyl ester has a pronounced, almost specific neurotropic/spasmolytic activity which is distinctly higher, by a factor of 50, than that of propiverine (see FIG. 1).

They are therefore referred to as m-cholinoceptor antagonists or parasympatholytics or—owing to their relaxing effect on smooth muscles—as neurotropic spasmolytics.

As a result, the class of compounds of formula I is also suitable for use as (i.e., for the preparation of a medicament for) a local anaesthetic and/or antiarrhythmic and/or antiemetic and/or nootropic (neurotropic) and/or for treatment/therapy of cardiovascular diseases and/or urinary incontinence and/or diarrhea and/or pruritus and/or alcohol and/or drug or medicament dependency and/or inflammations.

Rabies lyssavirus, formerly Rabies virus, is a neurotropic virus that causes rabies in humans and animals.

The aforesaid advantageous properties render the compounds of the invention useful as therapeutic agents with neurotropic properties.

Along with neurotropic sodium vitamins, diclofenac effectively removes the pain syndrome and significantly reduces the level of inflammation in the pathology of the musculoskeletal system and neuralgia.

Less virulent strains are strictly neurotropic and cause no further organ damage, as opposed to the more virulent strains.

Thus, an acute EBV infection may be confused with a primary HIV infection, rubella virus infection, cytomegalovirus infection, infection by classical hepatitis viruses, toxoplasmosis, leptospirosis, infection by various neurotropic pathogens and with leukaemia or a lymphoma.

Other reported effects: antioxidant , chemoprotective , neurotropic , anti-aging , anti-atherosclerosis , rheumatoid arthritis , obesity , liver cancer , stress , fatigue .

Preferably the pharmaceutical compositions according to the invention are suitable for controlling pain, in particular chronic and/or non-chronic pain, as a local anaesthetic, an anti-arrhythmic, anti-emetic and/or nootropic (neurotropic), for the treatment of inflammatory and/or allergic reactions, cardiovascular diseases, urinary incontinence, diarrhea, gastritis, ulcers, shock, migraine, narcolepsy, obesity, asthma, glaucoma, tinnitus, hyperkinetic syndrome, pruritus, alcohol and/or drug and/or medicine abuse and/or dependency and/or inflammation and/or depression and/or to increase alertness, to increase libido and/or for the treatment of neurodegenerative diseases, in particular Parkinson's disease and/or Huntington's chorea, for the treatment and/or prophylaxis of epilepsy, schizophrenia, Alzheimer's disease, stroke, cerebral ischemia, cerebral infarct and/or cerebral oedema and/or for anxiolysis and/or anaesthesia.

The pharmaceutical composition according to claim 10, further comprising a therapeutic agent selected from chemotherapeutic agent, an anti-inflammatory agent, an immunomodulatory agent, a neurotropic factor, an agent for treating cardiovascular disease, an agent for treating liver disease, an anti-viral agent, an agent for treating blood disorders, an agent for treating diabetes, and an agent for treating immunodeficiency disorders.

We will use new cultivation techniques mimicking neuronal ageing in vitro and cell type specific metabolic labeling in vivo to investigate CD8+ T cell/neuron interaction during systemic infection with neurotropic Langat virus.

In recent years, EHV-1-associated neurological diseases, for which a “neurotropic” strain of EHV1 is held responsible, have been reported with increasing frequency and severity of the clinical disease.