Translation of "Transepithelial" in German

These complications could probably be avoided by choosing a transepithelial approach.

In the tests the cells' so-called transepithelial resistance is measured.

The dry extract according to the invention was examined for transepithelial electrolyte transport.

In this, the extent to which the tight junctions are opened or closed are shown both by the transepithelial electrical resistance (TEER) and by the permeation of radioactive tracers (14 C-mannitol) through the cell monolayer.

It is evident that the transepithelial electrical resistance falls markedly on use of copolymer 1, 2 and 4 to 6, whereas only a slight reduction is observed with comparison polymer 3.

Results: Oxidative stress by 2mM H2O2 led to a 3 times increase in transepithelial flux of FITC-dextran.

In this study, we demonstrate equations for converting radioactivity data to various parameters that provide key preliminary information regarding transepithelial transport.

The transepithelial resistance is measured (a measure of the density of the cells or the permeability of substances).

In the course of the graduate school life science projects dealing with secretion and transepithelial transport processes should be carried out, especially with regard to the barrier function of the epithelium.

The transepithelial transport of liquid is mediated by the ion channels ENaC (Na +) and CFTR (for Cl-).

The preparation is preferably essentially isotonic and has no negative effect on the transepithelial electrical resistance (TEER) in a calu-3 pulmonary epithelial cell model, which is a measure of the tolerability of the active agent and the formulation in relation to the impact on cellular vitality, and, in human pulmonary cells, the composition does not result in a significant increase of interleukin-8, an inflammation biomarker.

The transepithelial resistance (RT) was adjusted using a computer program (Physiology Instruments San Diego, Calif., USA) at 640 ms, bipolar 10 mV potential via the monolayer measured in accordance with Ohms Law.

Besides the bidirectional permeability of test and reference substances (references: low permeability: PEG 4000; high permeability: clonidine; directional permeability: digoxin), the integrity of the cell monolayer is ensured by determining the transepithelial resistance (TEER).

A: Replacing 40 mM NMDG+ with an equimolar amount of NH 4 + leads to a significant rise in the transepithelial current.

Typically, one can already observe a discrete transepithelial current now, corresponding to the basic activity of the epithelial sodium pump (Na + /K + -ATPase).

The mean values of the transepithelial current (±SEM) over time from 13 individual measurements on three different epithelia were plotted as in FIG.

According to patent application EP 2 009 023 A1, the so-called transepithelial electrical resistance (TEER) test was used for the screening of anti-lung oedema active ingredient candidates.

Moreover, it could be shown that the transepithelial electrical resistance (TEER), as a measure for the permeability of the monolayer when cells are incubated with quaternized polymers, also decreases at pH 7.4, whereas this is not so for the original aminoalkyl methacrylate copolymer E.

For example, the degree of transepithelial transport is represented by NCs or molecules transported per cell, the efficiency of transporting content that binds or enters cells is represented by percentage of cell-associated NCs or molecules transported, and the rate of transport, which allows for comparison of permeability between different solutes, is signified by Papp.

To determine barrier properties transepithelial resistance (TER) was measured in the follow-up of 3 days.

It is expected that the research enabled by the newly developed sensors will provide fundamentally new insights into the molecular processes and signaling pathways in the alveoli and the transepithelial transport processes.