Translation of "Translocate" in German

This embodiment of the invention makes use of the fact, that different homeodomains and homeoproteins translocate via the cell membrane, when they are added to the culture medium, to eventually enter the nucleus.

In the second conveyor plane, the cartridges can be conveyed horizontally, in order to translocate each of these into the region of the printing couples of the specific printing unit for which the conveyed printing plates are being supplied.

E1A-modified adenoviruses as used herein, are adenoviruses which (a) do not replicate in YB-1 nucleus-negative cells or show a reduced, preferably a strongly reduced replication in YB-1 nucleus-negative cells compared to the respective wildtype, (b) transactivate at least one viral gene, whereby the gene is in particular selected from the group comprising E1B55, E4orf6, E4orf3 and E3ADP, and/or (c) do not translocate cellular YB-1 through the adenovirus into the nucleus.

Due to the deletion of CR3 in dl520, this adenovirus cannot translocate cellular YB-1 into the cell's nucleus, which is also referred to herein as translocation, and is thus not in a position to replicate in cells which are YB-1 nucleus-negative, and is thus a virus which can be used in accordance with the present invention, whereby this virus comprises the transactivation required in accordance with the present invention.

Due to the deletion of CR3 in d1520 this adenovirus cannot translocate cellular YB-1 into the cell's nucleus which is also referred to herein as translocation, and is thus not in a position to replicate in cells which are YB-1 nucleus-negative and is thus a virus which can be used in accordance with the present invention, whereby this virus comprises the transactivation required in accordance with the present invention.

E1A-modified adenoviruses are to be understood as those which (a) have, in YB-1 nucleus-negative cells, a reduced or no replication at all compared to wildtype, (b) have a transactivation activity on at least one viral gene, whereby the gene is particularly selected from the group comprising E1B-55kDa, E4orf6, E4orf3 and E3ADP, and/or (c) do not translocate cellular YB-1 into the nucleus by the adenovirus.

The reduction in the activity of the modified botulinum toxins according to the present invention to 20-30% as compared to the reference sample is obviously based on the reduced ability of the toxin to bind to the target cells and on the reduced ability to translocate the toxin into the target cells.

The activated IKK induces the phosphorylation and thus the proteolysis of p100 to p52, which in turn can translocate in the complex with the RELB into the cell nucleus and act there as a transcription factor.

In an exemplary embodiment, a common mechanical seat-valve operator is provided in the volume booster. The operator can be translationally moveable to the housing structure. In an exemplary embodiment, the seat-valve operator is configured to operate, the de-aeration seat-valve as well as the aeration seat-valve as well as the amplification seat-valve and to successively translocate them in order to create a controlled amount of air in relation to value at the timing within the pneumatic actuator.

They discovered that plants with the early-flowering Oxford allele and leaves with just a few leaflets formed seeds that weighed less than those from plants with more leaflets, suggesting that these plants may be less able to produce or translocate sufficient resources to their seeds.

To test this idea, the scientists selected plants from their pool which flower early and had either "young" leaf forms with few leaflets or "adult" leaf forms with many leaflets, as would normally happen. They discovered that plants with the early-flowering Oxford allele and leaves with just a few leaflets formed seeds that weighed less than those from plants with more leaflets, suggesting that these plants may be less able to produce or translocate sufficient resources to their seeds.